Circwhsc1
WebIntroduction: Extracellular vesicles (EVs)-mediated cell-to-cell communication is crucial for hypoxia-induced cell proliferation and tissue repair, but its function in endogenous … WebJan 5, 2024 · CircWHSC1 is a novel circRNA that accelerates ovarian cancer progression. Nevertheless, the function of circWHSC1 in regulating breast cancer (BC) is elusive. Here, quantitative reverse transcription …
Circwhsc1
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WebDec 1, 2024 · CircWHSC1 was a sponge of miR-212-5p in TNBC cells. (A) The subcellular localization of circWHSC1 in TNBC cells was determined by qRT-PCR. (B) The binding … WebDec 1, 2024 · CircWHSC1 [170] and circPUM1 [77] were reported to not only promote EOC cell proliferation, migration and invasion by sponging miRNAs but also act on the peritoneum in an exosome-dependent manner ...
WebJul 27, 2024 · CircWHSC1 is an independent indicator of poor prognosis in NSCLC patients, and functions as a ceRNA of miR-296-3p to up-regulate AKT3, consequently promotes NSCLC cell growth and metastasis. Targeting circWHSC1 might be a prospective strategy for diagnosis, therapeutics, and prognosis of NSCLC. WebOct 8, 2024 · Exosomal circWHSC1 shifts the morphology of peritoneal mesothelial cells to fibroblast-like and upregulates N-cadherin and MUC1 in peritoneal mesothelial cells. Furthermore, the peritoneal injection of …
WebJan 6, 2024 · CircWHSC1 functioned as the sponge for miR‐142‐3p, which directly targeted HOXA1. Inhibition of miR‐142‐3p ameliorated the effects of circWHSC1 knockdown on HCC cell proliferation and metastasis. Moreover, miR‐142‐3p overexpression restrained the growth and motility of HCC cells, with HOXA1 elevation reversing the impacts. ... WebcircWHSC1, miR-532-3p, and latent transforming growth factor-β binding protein 2 (LTBP2) was conrmed by luciferase reporter and biotinylated RNA pull-down assays. A nude mice …
WebDec 29, 2024 · CircWhsc1, a hypoxia-inducible circRNA, is highly expressed in cardiac ECs. (A) Screened circRNAs that are highly expressed in neonatal rodent hearts, …
WebDec 1, 2024 · The role of circWHSC1 in vivo was verified by tumor xenograft assay. The relationship between miR-212-5p and circWHSC1 or AKT3 was verified via dual-luciferase reporter and RNA pull-down assays. CircWHSC1 was upregulated in BC tissues and cells. Also, circWHSC1 could discriminate BC tissues and paracancerous normal tissues. highest protein vegetables and fruitsWebJan 5, 2024 · CircWHSC1 is a novel circRNA that accelerates ovarian cancer progression. Nevertheless, the function of circWHSC1 in regulating breast cancer (BC) is elusive. … highest ps5 resolutionWebOct 30, 2024 · CircWHSC1 promotes cell viability, migration and invasion ability in ovarian cancer. QRT-PCR indicated that expression level of … highest prot enchantmentWebDec 31, 2024 · We found that circWhsc1 was enriched in neonatal mouse hearts, particularly in cardiac ECs, and was further upregulated both in ECs and EC-derived EVs under hypoxic conditions. When cocultured with hypoxia-preconditioned neonatal ECs or their secreted EVs, both neonatal and adult CMs exhibited an increased proliferation rate … how hall effect thrusters workWebExosomal circWHSC1 can be transferred to peritoneal mesothelial cells and promotes peritoneal dissemination. Conclusions Our study demonstrates the highly expressed circWHSC1 in ovarian cancer promotes tumorigenesis by sponging miR-145 and miR-1182, and its exosome forms induce tumor metastasis through acting on peritoneal mesothelium. highest provincial taxes in canadaWebMar 2, 2024 · The interplay among circWHSC1, miR-532-3p, and latent transforming growth factor-β binding protein 2 (LTBP2) was confirmed by luciferase reporter and biotinylated … highest protein protein powderWebIntroduction. Non-small cell lung cancer (NSCLC) takes up 80% of all lung cancer cases and is the most common type of human lung cancer. 1 Although surgery, radiotherapy, and chemotherapy have great progress, the 5-year survival rate of NSCLC patients is still less than 19% due to relapse and drug resistance, and the lack of sensitive and efficient early … highest protein whey isolate