Ionophore compounds

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August undefined, 2024

Ionophores are chemical compounds that reversibly bind and transport ions through biological membranes in the absence of a protein pore. This can disrupt the membrane potential, and thus these substances could exhibit cytotoxic properties. Ionophores modify the permeability of biological … Meer weergeven In chemistry, an ionophore (from Greek ion and -phore 'ion carrier') is a chemical species that reversibly binds ions. Many ionophores are lipid-soluble entities that transport ions across the cell membrane. Ionophores Meer weergeven Several chemical factors affect the ionophore activity. The activity of an ionophore-metal complex depends on its geometric configuration and the coordinating sites and atoms which create coordination environment surrounding the metal … Meer weergeven • Fluka ionophores for ion-selective electrodes • Medical Information database Reference.MD • Structures and Properties of Naturally Occurring Polyether Antibiotics, J. Rutkowski, B. Brzezinski; open access review article Meer weergeven Biological activities of metal ion-binding compounds can be changed in response to the increment of the metal concentration, and based on the latter compounds can be classified as "metal ionophores", "metal chelators" or "metal shuttles". If … Meer weergeven Ionophores are widely used in cell physiology experiments and biotechnology as these compounds can effectively perturb … Meer weergeven • Siderophore • Protonophore • Chelation Meer weergeven Webionophore ( aɪˈɒnəˌfɔː) n (Elements & Compounds) a chemical compound capable of forming a complex with an ion and transporting it through a biological membrane [C20: from ion + -o- + -phore] Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

Differential in vitro activities of ionophore compounds against ...

Web21 aug. 2024 · An ionophore is a compound that can transport ions (like zinc) across biological cell membranes. Since zinc regulates adaptive immune cell function, these compounds can help maintain higher levels of intracellular zinc and decrease the … Web2 aug. 2016 · Ionophore antibiotics are classical coccidiostats used to prevent microbial-associated disease in populations of animal livestock. In recent years, these compounds have been additionally considered for the treatment of cancer. Ionophore antibiotics act … can both spouses open hsa

Differential in vitro activities of ionophore compounds against ...

Web1 okt. 2003 · Ionophores (such as monensin, lasalocid, laidlomycin, salinomycin and narasin) are antimicrobial compounds that are commonly fed to ruminant animals to improve feed efficiency. These ... WebIonophores are feed additives used in cattle diets to increase feed efficiency and body weight gain. They are compounds that alter rumen fermentation patterns. Ionophores have been used widely in the beef and poultry industry for improved feed efficiency and … Webionophore: [ i´on-o-for″ ] any molecule, as of a drug, that increases the permeability of cell membranes to a specific ion. can botox affect kidney function

Potential safety risks in pet food ingredients PFIAA

The characterisation of polyether ionophore veterinary drugs by …

Web22 dec. 2024 · Polyether ionophores are natural products that display antibacterial activity—but they also show activity against mammalian cells, which has limited their development as clinical antibiotics. WebCarbonate Ionophore VII is used in chromatography. It is an ion sensor compound used in ionophore potentiometric for ISE (ion-selective electrodes). Carbonate Ionophores for Ion Selective Electrodes Lithium Ionophore VIII Lithium Ionophore VIII is a carrier for … canbothue.gdt.gov.vnWebIonophore compounds include monensin (Coban, Rumensin, Rumensin CRC, Kexxtone), lasalocid (Avatec, Bovatec), salinomycin (Bio-cox, Sacox), narasin (Monteban, Maxiban), maduramicin (Cygro), laidlomycin (Cattlyst), and semduramicin (Aviax). can botox affect pregnancy

"WebIonophores are a diverse class of synthetic and naturally occurring ion transporter compounds which demonstrate both direct and in-direct antimicrobial properties against a broad panel of bacterial, fungal, viral and parasitic pathogens. In addition, ionophores can regulate the host-immune response … " - Ionophore compounds

Ionophore compounds

Rapid quantification of ionophores in feeds by liquid …

WebWe have found that the addition of ammonium acetate to the HPLC mobile phase, in conjunction with ‘cone voltage’ or ‘skimmer’ assisted fragmentation, is a convenient way of producing additional diagnostic ions from polyether ionophore compounds, without … Webionophore ( aɪˈɒnəˌfɔː) n (Elements & Compounds) a chemical compound capable of forming a complex with an ion and transporting it through a biological membrane [C20: from ion + -o- + -phore] Collins English Dictionary – Complete and Unabridged, 12th Edition …

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WebIonophores are compounds which can facilitate the migration of ions across biological membranes. Ions, being electrically charged, cannot by themselves cross the hydrophobic interior of biological membranes. Ionophores usually have a polar inner moiety, and a non-polar outer moiety which can span or cross the hydrophobic interior of the membrane. Web29 okt. 2008 · Macrocyclic compounds, such as crown ethers, azacrown ethers, thiacrown ethers, calixarenes and porphyrins, which act as ionophores in lead(II) ion-selective electrodes, are systematically summarized based on the latest literatures. The molecular structure characteristics of the ionophores are generalized. The modification regulations …

Web23 dec. 2024 · Recycling polyether ionophore components to improve antibiotic selectivity. Modular synthesis of unnatural polyether ionophores results in compounds with potent antibiotic activity and reduced effects/toxicity to mammalian cells. Published Dec 23, 2024. WebThe structure of four ionophores used as anticoccidials, monensin, salinomycin, lasalocid and narasin are given in Table 1. Maduramycin is a further compound currently in use at 5 ppm in feed (Kantor et al., 1984). The ionophores have a wide spectrum of activity, but rather a narrow range of safety. However, despite reported monensin-resistant ...

WebIonophores and auxiliary components (polymers, plasticizers, additives) used in potentiometric or optical sensors have different specifications than materials used for other applications. It is essential that the product is free of disrupting impurities, such as metal … WebIonophore compounds contain carboxylic acid, multiple cyclic ethers, and multiple oxygen-containing groups, as shown in Figure 1. Such compounds form stable cyclic complexes Figure 2. Mass spectrum of lasalocid. Figure 3. Chromatography of ionophores.

Web5 mrt. 2024 · Ionophores interact with ion transportation within the parasite, hence their name which is derived from the Greek 'ion phoros', meaning 'ion carrier'. Ionophores transport ions (e.g. sodium (Na + ), potassium (K + ), hydrogen (H +) etc.) across …

WebThe natural polyether ionophore antibiotics may be important chemotherapeutic agents. Among them, kijimicin represents an important type of ionophore compound because it inhibits Eimeria tenella and human immunodeciency virus. The ionophore monensin displays potent activities against several coccidian parasites including the opportunistic ... can both spouse have hsaWeb7 mrt. 2008 · As ionophores form complexes with cations and mediate their transport across the cell membrane in response to diffusion gradient, mitochondrial failure and depletion of cellular adenosine triphosphate … can both unmarried parents file hohWebWe have found that the addition of ammonium acetate to the HPLC mobile phase, in conjunction with ‘cone voltage’ or ‘skimmer’ assisted fragmentation, is a convenient way of producing additional diagnostic ions from polyether ionophore compounds, without compromising the overall sensitivity. can botox affect your eyesWebIonophores are compounds which can facilitate the migration of ions across biological membranes. Ions, being electrically charged, cannot by themselves cross the hydrophobic interior of biological membranes. Ionophores usually have a polar inner moiety, and a … can botometer be used in facebookWeb4 mrt. 2024 · The most known compound of the HQ class is 7-iodo- 5-chloro-8-hydroxyquinoline (CQ) that was first used as an antibiotic and more recently has been studied for the repurposing in different diseases ranging from neurodegenerative disorders to cancer ( Oliveri, 2024 ). fishing kentucky lake bcWeb30 sep. 2015 · Dear Colleagues, Ionophore-based potentiometric sensors or ion-selective electrodes (ISEs) are chemical sensors where host-guest chemistry is utilized to achieve high selectivity to specific ions of interest. A unique feature of ISEs is that they provide information about the free ion concentration (ion activity), which is highly relevant in, e ... can botox affect your eyesightWeb27 aug. 2024 · Ionic liquids are finding more and more wide application as matrices in the creation of amperometric sensors. They are usually used in combination with various compounds: polymers, cellulose, carbon nanotubes, metal nanoparticles, or graphene. fishing kentucky