Population pharmacokinetics of polymyxin b
WebMy strengths lie in communication, data-driven decision making, and problem solving. As a collaborative and multidisciplinary researcher, I bring a unique perspective to solving … WebDec 14, 2024 · Population-Based Pharmacokinetic Model for Intravenous Polymyxin B: A Quantitative Framework to Predict Pharmacokinetic Estimates in Patients with Gram-Negative Infections
Population pharmacokinetics of polymyxin b
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WebJun 18, 2024 · The population PK was determined using NONMEM and Monte Carlo simulation was performed to evaluate the exposures of different dosing regimens. Results. The PK analyses included 342 steady-state concentrations and a two-compartment model was optimal for polymyxin B PK data modelling. WebNov 15, 2024 · The aim of this study was to assess polymyxin B pharmacokinetics (PK) in patients with varying degrees of renal dysfunction and in patients who require ... (2024) …
WebVoriconazole (VRC) is used as first line antifungal agent against invasive aspergillosis. Model-based approaches might optimize VRC therapy. This study aimed to investigate the predictive performance of pharmacokinetic models of VRC without pharmacogenetic information for their suitability for model-informed precision dosing. Seven PopPK models … WebDec 14, 2024 · Polymyxin B is used as a last treatment resort for multidrug-resistant Gram-negative bacterial infections. The objectives of this study were to examine the population …
WebJun 1, 2024 · The aim of this study was to assess the population pharmacokinetics (PK) of intravenous polymyxin B in patients with variable total body weights and create a … WebApr 6, 2024 · Polymyxin B is a "last-line-of-defense" antibiotic approved in the 1960s. However, the population pharmacokinetics (PK) of its four main components has not been reported in infected mice.
WebApr 11, 2024 · This indicated that patients with MET exon 14 skipping mutation might be a better target population, which also supported our further study in Part B. However, due to the limited sample size and short follow-up duration, the activity of BPI-9016M in patients with both c-MET overexpression and MET exon 14 skipping mutation still needs further …
WebFeb 1, 2024 · Wang P, Zhang Q, Zhu Z, et al. Population Pharmacokinetics and Limited Sampling Strategy for Therapeutic Drug Monitoring of Polymyxin B in Chinese Patients … imbuing the headpiece tbc classicWebSandri AM, Landersdorfer CB, Jacob J, et al. Population pharmacokinetics of intravenous polymyxin B in critically ill patients: implications for selection of dosage regimens. Clin Infect Dis. 2013;57(4) ... Dubrovskaya Y, et al. Population pharmacokinetics of polymyxin B. Clin Pharmacol Ther. 2024;104(3):534–538. doi:10.1002/cpt.981. 32. list of jk rowling\\u0027s awardsWebApr 6, 2024 · Polymyxin B compartmental population pharmacokinetics model [ Time Frame: From immediately prior to a dose of therapy through 8 hours after therapy, … imbuing slayer helmWebR-Praziquantel Integrated Population Pharmacokinetics in Preschool- and School-Aged African Children Infected with Schistosoma mansoni and S. haematobium and Lao ... list of jimmy swaggart songsWebNov 1, 2024 · Free Online Library: Evaluation of a Sequential Antibiotic Treatment Regimen of Ampicillin, Ciprofloxacin and Fosfomycin against Escherichia coli CFT073 in the Hollow … imbuir armas terrariaWebApr 11, 2024 · The target population of this study was Chinese septic patients with or without acute kidney injury, which were divided into five groups including group A of 12 patients (receiving meropenem) without acute kidney injury, group B of 12 patients (receiving meropenem) without renal replacement therapy for acute kidney injury, group C … imbuing touch 5eWebOct 1, 2024 · However, the correlation between polymyxin B pharmacokinetics (PK) and creatinine clearance (CrCL) is poor. This study aimed to develop a population PK model of … imbuing tower poe